Serum melatonin concentrations in coronary heart disease patients with hypercholesterolaemia

Abstract

This investigation was undertaken to determine the serum melatonin concentrations in coronary heart disease patients (CHD) with hypercholesterolaemia. Hypercholesterolaemia is a contributing factor to atherogenesis in CHD. Melatonin suppresses cholesterol synthesis. The preliminary results indicate that melatonin levels seem to be suppressed in CHD patients with hypercholesterolaemia.